Osteoporosis can occur in anyone, and can take many different forms. Let’s take a closer look.
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Bei einem gesunden Knochen findet ständig ein ausgeglichener Stoffwechsel zwischen Knochenabbau und Knochenaufbau statt. Bei der Osteoporose ist der Knochenaufbau und der Knochenabbau der Knochenmasse im Ungleichgewicht . Es wird mehr Knochenmasse durch Osteoklasten abgebaut, als von den Osteoblasten wieder aufegebaut wird. English: Osteoporosis is a disease of bone that leads to an increased risk of fracture. In osteoporosis the bone mineral density (BMD) is reduced, bone microarchitecture is disrupted, and the amount and variety of proteins in bone is altered. Osteoporosis is most common in women after menopause, when it is called postmenopausal osteoporosis, but may also develop in men. Trabecular bone is the sponge-like bone in the ends of long bones and vertebrae. Cortical bone is the hard outer shell of bones and the middle of long bones. Because osteoblasts and osteoclasts inhabit the surface of bones, trabecular bone is more active, more subject to bone turnover, to remodeling. Common osteoporotic fracture sites, the wrist, the hip and the spine, have a relatively high trabecular bone to cortical bone ratio. These areas rely on trabecular bone for strength, and therefore the intense remodeling causes these areas to degenerate most when the remodeling is imbalanced.
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Just because you break a bone doesn’t mean you have osteoporosis! Here’s how your doctor will determine if you’re among the 10 million with this disease.Watch More Health Videos at Health Guru: www.healthguru.com
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FDA has issued an early communication to healthcare professionals about a possible association between bisphosphonate drugs, which are used to treat osteoporosis, and atrial fibrillation. This issuance is part of FDA’s commitment to keep the public informed about ongoing safety reviews of drugs, even when the evidence isn’t conclusive. In this case, the communication is based on two studies of women treated with the bisphosphonates Reclast (zoledronic acid) and Fosamax (alendronate). They were reported in the May 3, 2007 issue of the New England Journal of Medicine. In both studies, more women who received the bisphosphonates developed serious atrial fibrillation than those who received placebos. There was no significant difference between the two groups in the rate of non-serious fibrillation. FDA has reviewed these studies, along with premarket studies and postmarketing reports on bisphosphonate drugs, and at this point, it is not clear how the data on serious atrial fibrillation should be interpreted. Because of this uncertainty, FDA is not recommending that healthcare providers or patients change the prescribing or use of these drugs at this time. FDA is gathering additional data that will allow for an in-depth evaluation of the atrial fibrillation issue for the entire class of bisphosphonates. As soon as the evaluation is finished, which may take up to 12 months, FDA will inform the public about the results and any new recommendations on prescribing or using these …
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Like many diseases, osteoporosis can be slowed, or even slightly reduced, with proper prescription medication.Watch More Health Videos at Health Guru: www.healthguru.com (more)
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rufusrajadurai.wetpaint.com This is an 3D medical animation video to show what is osteoporosis and how it cause weakness to bone and the effect of osteoblast and osteoclast cells in it.also it shows the later stage and diagnosis of osteoporosis
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